Does milk thistle affect the action and excretion of testosterone?

Good morning, I have a question: if someone uses hormone replacement therapy with testosterone (injections of Testosteronm Prolongatum Jelfa) and at the same time takes various supplements to support liver cleansing, eg milk thistle, will it not cause that testosterone will be metabolized faster in the liver and excreted from the body? And the second question: will the use of the sauna and heavy sweating not have the same effect that testosterone will be quickly excreted? Thank you for your reply