What is the difference between Medikinet 10mg and Medikinet CR 10mg?
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Olga Filits Pharmacist
3 years ago
The above-mentioned drugs are preparations that affect the central nervous system. It is used in patients with attention deficit hyperactivity disorder (ADHD). MEDIKINET in the form of tablets is a drug from which the rate of release of the medicinal substance is not intentionally modified. The medicinal substance is released quickly, after the breakdown of the tablet, and is absorbed in the stomach and upper section of the small intestine. This is the most commonly used type of tablets. MEDIKINET CR capsules with modified release. Cr stands for Control Release. This means that this form of the drug can release part of the dose faster and the rest gradually (the so-called multiphase system – a more complex release profile). The release of the active substance from Medikinet CR and the increase in its plasma concentration shows two phases: the initial one with a sharp elevation (as in "ordinary" immediate-release tablets, where on average after 1-2 hours a concentration peak is reached) - this guarantees obtaining the maximum concentration quite quickly, and the second phase with an increase in concentration occurring about 3 hours later, followed by a gradual decrease. The second phase occurs due to the release of the drug from the part of the capsule characterized by prolonged release - the phase of the so-called "plateau", that is, a stable concentration, lasts about 3-4 hours. I attach leaflets to read the information about medicines: https://www.gdziepolek.pl/produkty/47474/medikinet-cr-10-mg-kapsulki/ulotka/140584 https://www.gdziepolek.pl/produkty/47471/medikinet-10-mg-tabletki/ulotka/140589