MORPHINI SULFAS WZF
Hello
I would like to point out at the outset that the question and answers are for information and educational purposes. The photo is taken by me.
I have morphini sulfas wzf ampoules and it is 6 months out of date. Morphine was stored in ideal conditions - without access to light and in the refrigerator.
Should I still use ? Of course, please do not warn about the fact that it can be dangerous, etc., etc., because it is far from that, because for morphine to be really very toxic, hmm.. It would take about 4 years and I would be exposed to heat and strong daylight all the time. -yes
I think.
It is said that most painkillers that have expired even a few months, including opioids, only work with less "strength", but they still work.
What does "chatGPT" write;
Expired: 6 months
• In ideal conditions (cool, dark), such substances do not decompose suddenly.
• Morphine is a relatively stable alkaloid molecule, especially in the form of sulphate and aqueous solution – the breakdown is slow, especially when it does not come into contact with oxygen, light and heat.
What happens after the due date?
1. Effectiveness: may decrease slightly. Studies (e.g., the U.S. Shelf Life Extension Program) have shown that many drugs, including opioids, maintain >90% of their potency for several years after their expiration date if stored correctly.
2. Safety: no toxic metabolites are formed. Morphine does not break down into dangerous compounds – even after years, it only loses its potency.
3. Appearance of the solution: if it is not cloudy, there is no sediment, no change in color or smell – it can still be chemically stable.
Summary:
• Morphine expired by 6 months, stored in a refrigerator without access to light, probably still contains 90-100% of the active substance.
• The risk of toxicity is negligible or zero unless contamination or degradation of the solution has occurred (which can be observed visually).
• The potency may be slightly reduced, but the substance remains active.
• Purely chemical: YES, it can still be used – as long as it looks and smells like a fresh solution.
And as you can see, even I was wrong because morphine maintains its chemical stability for over 5 years without toxicity.
I wonder how it is with pills, but it seems to me that it is worse. I'm not asking ChatuGPT specifically - I'm curious from your knowledge if there are any assumptions you have:)
I invite you to a short discussion for those interested.