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Non-prescription medicines delivery across Europe.
Frequently ordered: potency boosters (sildenafil OTC), quit smoking aids.
Can Wellbutrin XR, Welbox and Bupropion Neuraxpharm be used interchangeably?
Good morning! I am currently taking Wellbutrin 150mg, but I have noticed the increasing availability of its substitutes: Welbox and Bupropion (...). I would like to ask whether these drugs can be used interchangeably - including bioavailability. Wellbutrin works well for me - I do not know if it is worth saving several dozen zlotys on a drug that can potentially work "worse" or less effectively. I would not like to spoil my current treatment history and its effects.
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I recommend the book Bottle of Lies - about generic drugs. It is not always Nocebo and in the case of Buproprion already more than one manufacturer has messed up with the Extended Release mechanism.
Ewa Pilch Pharmacist, Editor
2 years ago
According to the summary of product characteristics, the preparations have the same pharmacodynamic effect and can be used as substitutes. For any preparation, the manufacturer does not provide full bioavailability: - for Wellbutrin XR - the maximum concentration for bupropion is reached after about 5 hours, while the maximum concentration for hydroxybupropion is reached after about 7 hours, and for treohydrobupropion and erythrohydrobupropion after about 8 hours. At least 87% of the dose is absorbed: https://www.gdziepolek.pl/produkty/84068/wellbutrin-xr-tabletki-o-zmodyfikowanym-uwalnianiu/apteki - for Welbox - the maximum concentration for bupropion is reached after about 5 hours, while the maximum concentration for hydroxybupropion is reached after about 7 hours, and for treohydrobupropion and erythrohydrobupropion after about 8 hours. At least 87% of the dose is absorbed: https://www.gdziepolek.pl/produkty/105737/welbox-tabletki-o-zmodyfikowanym-uwalnianiu/apteki - for Bupropion Neuraxpharm - the maximum concentration for bupropion is reached after about 5 hours, while the maximum concentration for hydroxybupropion is reached after about 7 hours, and for treohydrobupropion and erythrohydrobupropion after about 8 hours. At least 87% of the dose is absorbed: https://www.gdziepolek.pl/produkty/112437/bupropion-neuraxpharm-tabletki-o-zmodyfikowanym-uwalnianiu/apteki More about what drug substitutes are, we wrote in the article: https://www.gdziepolek.pl/artykuly/czym-sa-zamienniki-lekow