Is Vivace a substitute for Triplixam?

Vivace 5 mg is not a substitute for Triplixam 5 + 1.25 + 5 mg. Both drugs are used to treat hypertension, however, they differ significantly in composition. Vivace contains ramipril - a prodrug, the active metabolite of which by reducing the formation of angiotensin II and inhibiting the breakdown of bradykinin, leads to the expansion of blood vessels. Triplixam contains as many as 3 active substances: perindopril, indapamide and amlodipine with antihypertensive effect, dilating blood vessels. The drug can be used, for example, in people in whom treatment with one substance was not effective enough. I enclose leaflets: https://www.gdziepolek.pl/produkty/87305/triplixam-5-mg-1-25-mg-5-mg-tabletki-powlekane/ulotka https://www.gdziepolek.pl/produkty/83701/vivace-5-mg-tabletki/ulotka We wrote about what drug substitutes are here: https://www.gdziepolek.pl/artykuly/czym-sa-zamienniki-lekow