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Lethal dose of morphine starts with as little as 200 mg. But there are tablets with 200 mg. How can that be. Are there different strengths of morphine ?
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Aleksandra Kowalczyk Pharmacist, Editor
4 months ago
The lethal dose of morphine is about 120-200 mg and may vary depending on the patient's age, body weight, current health condition and tolerance to morphine. People addicted to morphine can tolerate higher doses of this substance without experiencing symptoms of poisoning. The substance can be absorbed from the digestive system to varying degrees, which also affects its final concentration in the blood.
The potency of a given morphine preparation depends on its dose and the patient's tolerance to the drug.
There are tablets on the market containing morphine in a dose of 200 mg. However, it is worth noting that these are modified-release tablets. These types of preparations do not immediately release the entire dose of the substance they contain. Depending on the drug and the modifications used in the tablet, part of the dose may be released more quickly and part gradually. This allows you to obtain the right concentration of the substance in the body for a longer period of time, without the need for frequent use of lower doses of the drug.
Therefore, modified or extended-release tablets must not be divided, crushed or chewed under any circumstances. Taking a damaged tablet may result in an excessively high, potentially fatal dose of the drug.
If you take a damaged tablet, you should go to the emergency room as soon as possible.
I attach related materials:
https://www.gdziepolek.pl/kategorie/narkotyczne-leki-przeciwbolowe-opioidy