Good morning. Is it safe to use Trittico xr together with pregabalin for neurosis? Such drugs were prescribed by a doctor. I was scared because I read information on the Internet that both drugs used can cause depression? Is this true and how to minimize the risk of interaction? Best regards
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Klaudia Ćwiąkała Pharmacist, Editor
7 months ago
Trittico XR (or trazodone) and pregabalin are drugs that are often used to treat anxiety disorders, depression and sleep disorders. The combined use of these drugs is acceptable, but requires caution and close medical supervision, as their sedative effects and potential side effects (e.g. sedation, fatigue) may be worsened.
Pregabalin may cause depressive symptoms in some patients, but this is a rare side effect that may occur at the beginning of treatment. Trazodone, on the other hand, has an antidepressant effect. It is worth bearing in mind that in the first weeks of depression treatment, you may experience a deterioration in mood or suicidal thoughts.
To minimize the risk of interactions and side effects, you should:
- use the medication as prescribed by your doctor - initially your doctor will probably recommend a gradual increase in the dose,
- monitor the symptoms and if you observe disturbing changes, report them to the doctor,
- avoid alcohol, which can increase the sedative effect of both drugs,
- take care of your lifestyle - regular exercise, a healthy diet and relaxation techniques can support treatment and reduce the risk of side effects.
I have attached helpful materials:
https://www.gdziepolek.pl/artykuly/czy-mozna-laczyc-leki-ze-soba
https://www.gdziepolek.pl/artykuly/czy-bac-sie-dzialan-niepozadanych-lekow