Hello good morning I would like to know aripiprazole 5mg once a day taken in the morning is it true that it is a dopaminergic stimulant ?
I mean the dosage of 5mg.
That is, it normalizes the dopaminergic system at this dose??
Or does it activate, stimulates dopamine??
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Joanna Dunajska Pharmacist, Editor
10 months ago
Aripyrazole has a unique mechanism of action. A large body of evidence indicates that, depending on the clinical situation of the selected region in the brain, aripiprazole may behave either as a partial agonist or as a dopamine D2 receptor antagonist. In the case of dopamine deficiency, aripiprazole may exhibit agonist effects, stabilizing the dopaminergic system, as a result of which a beneficial cognitive effect, beneficial effect on negative symptoms and behavior control is observed (usually higher doses of aripiprazole (dose 30 mg/day are needed to achieve such a clinical effect). In the case of excess dopamine, aripiprazole competes with dopamine for binding to the D2 receptor, i.e. it acts antagonistically.
I attach the source:
https://journals.viamedica.pl/psychiatria/article/view/53926/42432
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