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Is it possible to combine medical marijuana therapy with SSRIs?
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Anna Lewandowska Pharmacist, Editor
15 months ago
Combining medical marijuana therapy with SSRIs (serotonin reuptake inhibitors) is problematic because in many cases it is difficult for doctors to choose the right pharmacotherapy (m.in. due to the patient's symptoms), let alone combine it with cannabis drugs.
In addition, the cannabinoids in medical marijuana can increase the concentration of SSRIs in the body, which can cause or increase the severity of side effects associated with basic pharmacotherapy. However, if the dose of drugs and marijuana is properly selected, such a situation may not occur at all.
Studies conducted so far on medical marijuana and depression mainly include patients with drug-resistant depression that does not respond to pharmacological treatment, e.g. SSRIs, m.in. a study conducted in the USA in 2016 on the effects of medical marijuana on patients with depression showed that the subjects experienced a significant improvement in well-being and a reduction in most symptoms associated with depression. In addition, cannabis also benefited patients' sleep by making it easier to fall asleep and improving sleep quality.
In conclusion, the use of medical marijuana and antidepressants is possible, but requires individual adjustment of both therapies to the patient's symptoms. Close cooperation between doctor and patient is also important, as this is the only way to avoid serious side effects and achieve the best treatment results.
I also encourage you to read materials on similar topics:
https://www.gdziepolek.pl/artykuly/marihuana-z-apteki
https://www.gdziepolek.pl/artykuly/jak-wyglada-leczenie-marihuana-medyczna
https://www.gdziepolek.pl/artykuly/czym-rozni-sie-cbd-od-thc-marihuana-medyczna-olejki-cbd
https://www.gdziepolek.pl/blog/kiedy-medyczna-marihuana-wroci-do-aptek
The pharmacist claims that you can use the medical marijuana drug with SSRIs, and in the information from English Internet forums it is written like a bull that you can't combine, especially with fluoxetine, I wonder who is right. As I know life, this comment will be deleted in a short time.